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TBTU is an aminium coupling reagent used for amide and ester synthesis. TBTU is a stable, efficient and reactive reagent suitable for solution and solid-phase peptide synthesis. TBTU finds application in the synthesis of biologically active peptides, such as azapeptides.
TBTU is a coupling reagent used for solid-phase peptide synthesis. The compound has been used to study ten different phosphonium and uronium salt-based coupling reagents, which are used to synthesize four peptides.
A new and efficient method for the homologation of urethane protected α-amino acids to its β-homomers by the Arndt-Eistert method using TBTU as a coupling agent is described. Several Fmoc-/Boc-/Z-protected α-amino diazoketone derivatives have been obtained as crystalline solids in good yield. The method is found to be rapid and stereospecific.
Oman, Bahrain, Abu Dhabi, Ajman, Al Ain, Dubai, Ras Al-Khaimah, Fujairah, Sharjah, Umm Al Quwain, Ruwais, Mina Zayed, Khalifa Port, Kizad, Jebel Ali, Port Rashid, Khor Fakkan, Sharjah Creek, Port of Hamriyah, Mussafah Port, Saqr Port, Dibba Port, Jebel Dhanna, Mina Al Hamriya, and all major UAE ports.